The Cell and Gene Bank will provide DNA from standardized reference B-LCL for use as positive and negative controls for workshop projects using SSOP and SBT typing systems, those studying single nucleotide polymorphism and microsatellite markers, and those studying minor histocompatibility antigens. The Cell Bank will also distribute selected reagents (e.g., CEPH family cells, cells expressing null alleles, SNP typing kits) to participants in specific workshop components. Additional support activity provided by the Cell and Gene Bank will be defined by Component Chairs and their working groups as workshop protocols and procedures are developed.

The first two tables below show the current reference panels that have been assembled for use in SSOP and SBT typing assays developed by the SSOP and SBT Typing Technology Core. DNA from these reference cells is distributed to participating laboratories for use as positive and negative controls to monitor the specificity of primers and probes. The third table shows the current inventory of cloned HLA class I genes in the IHWG Gene Bank. The fourth table shows the current inventory of HLA-transduced cell lines in the 13th IHWG Cell Bank. These HLA transfectants have been generated for the isolation and study of mHA specific CTL clones.

A*0221, 7403, 2606, 1103, 2408; 0304
B*1404, 1528, 1533, 1805; 3507, 3912, 4015, 5505
Cw*0703, 0705, 0502, 0405, 0306, 1206, 0305